IMPORTANT TOPICS IN PHARMACOLOGY

TOPIC

MUST KNOW

DESIRABLE TO KNOW

GENERAL

pH, pKa, ionization

Bioavailability

First pass metabolism

Vd

PPB

Prodrugs

CYP substrates, inducers, inhibitors

Metabolic reactions

Formulas

First and zero order kinetics

TDM

Receptors types and examples

DRC

Pharmacogenetics

Clinical trials

Drug labels

Orphan drugs

Essential drugs

Enzyme inhibition (competitive, non-competitive and uncompetitive)

Types of antagonists

Pharmacovigilance

Evidence based medicine

ANS

AChE inhibitors

OP Poisoning

Sympathetic receptors location

Catecholamines table

Beta blockers

Anticholinergics

Alpha blockers

Glaucoma

Rabbit practicals

AUTACOIDS

Antihistaminics

PCM and aspirin poisoning

DMARDs

Gout

Migraine

PG actions

Other NSAIDs

CVS

Digoxin

New drugs for CHF

Drugs decreasing mortality in CHF

JNC 8 guidelines for hypertension

New antianginal drugs

Statins

Pulmonary hypertension

Antiarrhythmics

New hypolipidemic drugs

KIDNEY

K sparing diuretics

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Free water clearance

Vasopressin antagonists

ENDOCRINE

Somatostatin

GnRH agonist and antagonist

New antidiabetic drugs

Osteoporosis

SERM

OCPs

Mifepristone

Antithyroid drugs

Oral hypoglycemic agents

Adverse effect of steroids

SPRM

Anti-androgens

CNS

Short acting BZD

Parkinsonism

Multiple sclerosis

Antiepileptic drugs

Antipsychotic names and adverse effects

SSRI and SNRI

TCA poisoning

Lithium and mania

Newer hypnotic drugs

MAO inhibitors

Opioids

ANAESTHESIA

Local anaesthetics mechanism and special points

SCh and NDMRs

MAC and Bld gas partition coefficient

Colour coding of cylinders

Pin index system

Xenon

Halothane

Ketamine

Spinal anaesthesia

Neurolept analgesia

HEMATOLOGY

Anticoagulants specially new

Antiplatelets

Fibrinolytics

Iron deficiency anemia

Growth factors

RESPIRATORY

Bronchodilators 

DOC for different asthma types 

Theophylline

GIT

Peptic ulcer 

Crohn’s and Ulcerative colitis 

Metaclopramide, domperidone IBS

ANTIMICROBIALS

Important points (Review of Pharmacology 11^th edition/page:380-382)

Tuberculosis with RNTCP

Malaria

Mechanism of drug resistance

Beta lactams

Aminoglycosides

Fluoroquinolones

HIV

Hepatitis C

Tetracyclines

Macrolides

Cotrimoxazole

Leprosy

Antifungal

ANTICANCER

CCS and Non-specific drugs

General and specific adverse effects of anticancer drugs (Specially chemo-man cartoon)

Monoclonal antibodies

Tyrosine kinase inhibitors

Newer anticancer drugs

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IMMUNOLOGY

Cyclosporine

Tacrolimus

Monoclonal antibodies

Thalidomide

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SPECIAL TOPICS

New drugs approved in last 12 months (uses only)

Anti-obesity drugs

Erectile dysfunction

Anti-smoking drugs

Treatment of HIT

Treatment of hyperkalemia

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