Must know ‘New Drugs’ for NEET-PG

After sharing the complete list of New Drugs approved by the FDA in 2019, we have now up with a segregated list of important drugs. This list has been compiled by Dr. Gobind Rai Garg keeping in mind the upcoming NEET-PG exam.

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IMPORTANT DRUGS FOR NEET-PG 2020

The table includes the name of the drug, mechanism, route, and indication.

Drug	Mechanism	Route	Indication
Andexanet alpha*	Bind to Factor Xa inhibitors	Intravenous	To reverse overdose of rivaroxaban and apixaban
Apalutamide Darolutamide	Androgen receptor antagonist	Oral	Prostate carcinoma
Avatrombopag Lusutrombopag	Thrombopoietin receptor agonist	Oral	Thrombocytopenia in patients with chronic liver disease
Baloxavir marboxil*	Inhibit viral replication by inhibiting Cap-dependent endonuclease activity of viral polymerase	Oral	Single dose treatment of Acute uncomplicated influenza
Baricitinib	Janus Kinase inhibitor	Oral	Rheumatoid Arthritis
Brexanolone*	GABA-A modulator	Intravenous	Post partum depression
Elagolix	GnRH antagonist	Oral	Pain associated with endometriosis
Erenumab Fremanezumab Galcanezumab	Monoclonal antibody against CGRP	SC	Migraine prophylaxis
Esketamine*	Non-competitive NMDA antagonist	Intranasal	Treatment resistant depression
Ibalizumab*	MAb against CD4	IV	HIV
Lasmiditan*	5HT1F agonist	Oral	Acute severe migraine
Lofexidine	Alpha 2 agonist	Oral	To decrease opioid withdrawal symptoms
Pitolisant	H3 antagonist/inverse agonist	Oral	Narcolepsy
Pretomanid*	Inhibit mycolic acid synthesis	Oral	For XDR and MDR TB (in combination with bedaquiline and linezolide)
Romosozumab*	MAb against sclerostin	Subcutaneous	Post-menopausal osteoporosis
Semaglutide	GLP-1 agonist	Oral	Type 2 diabetes mellitus
Stiripentol	Increases GABAergic activity	Oral	Dravet Syndrome
Tafenoquine*	Free radical mediated killing of hypnozooites	Oral	Single dose radical cure of P. vivax malaria
Tecovirimat	Inhibit formation of extracellular viral forms	Oral	Small pox
Tenapanor	NHE-3 inhibitor	Oral	IBS with constipation
Tolvaptan	Vasopressin V2 receptor antagonist	Oral	To slow kidney function decline in adult polycystic kidney disease

*Highly important, you cannot skip

We hope this list will surely prove helpful to you for the upcoming NEET-PG exam.

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